A resident of San Diego, California, Dr. David M. Gilbert is a senior investigator with the San Diego Biomedical Research Institute (SDBRI), where he is head of the Laboratory of Chromosome Replication and Epigenome Regulation. A career professor, Dr. David M. Gilbert began lecturing in the Department of Biochemistry and Molecular Biology at the State University of New York (SUNY) in 1994.
Dr. Gilbert became an Associate Professor and then a Professor in the same department at SUNY until 2006, when he became the J.H. Taylor Distinguished Professor of Molecular Biology at Florida State University (FSU) and then joined SDBRI in 2021. Throughout his academic career, he was involved with numerous research projects and is credited with pioneering studies of how DNA replication is related to chromosome 3D structure and impacts how cells change from one type into another or into cancer cells. His independent research projects date back to 1995 when his first study, funded by the Milheim Foundation and the National Science Foundation, involved researching how DNA replication begins in mammalian cells.
Dr. Gilbert's active research projects initiated in the last five years have been funded by the National Cancer Institute, National Human Genome Research Institute and National Institute of General Medical Science-funded projects. As principal investigator, he researches chromosomal domains and discovered the impact of DNA replication on the structure and function of chromosomes.
Dr. David M. Gilbert has also developed web pages related to this field on sites such as ReplicationDomain.org, a database of chromosome domain properties that at one time hosted 100,000 visits per month, and FISH Finder, a program that calculates the distances between DNA sequences, as well as Undergraduate and Graduate Program websites.